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Drug Safety Update — United Kingdom

MHRA medicines recalls and defect notifications with batch numbers, Serious Shortage Protocols, new approvals and Drug Safety Update — updated daily, automatically. Last updated: 6 Oct 2026 08:50.

All Recalls and defects3 Serious shortages (SSP)2 New approvals1 Drug Safety Update

Sources: we track changes based on information published by the MHRA — medicines recalls and defect notifications, Drug Safety Update and approval announcements — and the Serious Shortage Protocols published by the NHS Business Services Authority. The UK is outside the EU, so European Commission decisions are not listed here.

22 Jan 2026Thursday 22 January 2026

open day ◀ ▶ 1 event · 1 important
Drug Safety Update Isotretinoin
The Commission on Human Medicines (CHM) has endorsed changes to the risk minimisation measures for isotretinoin, following a review of the impact of the measures implemented in 2023. We ask healthcare…
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8 Jan 2026Thursday 8 January 2026

open day ◀ ▶ 1 event · 1 important
The MHRA has reviewed the warnings regarding addiction, dependence, withdrawal, and tolerance for gabapentin, pregabalin, benzodiazepines, and z-drugs. The findings (detailed in the Public Assessment…
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17 Dec 2025Wednesday 17 December 2025

open day ◀ ▶ 1 event · 1 important
There is a risk of patient harm arising through medication error during a transition period where the original and new formulation of Rybelsus ® tablets, which have different stated mg doses but are b…
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4 Dec 2025Thursday 4 December 2025

open day ◀ ▶ 1 event · 1 important
Idiopathic intracranial hypertension (IIH) has been very rarely reported in patients treated with mesalazine. Following a recent review, warnings for IIH are being added to the product information for…
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27 Oct 2025Monday 27 October 2025

open day ◀ ▶ 1 event · 1 important
Drug Safety Update Isotretinoin
The Commission on Human Medicines (CHM) has endorsed changes to isotretinoin prescribing guidance. In addition, CHM is seeking further information from dermatology services who prescribe isotretinoin …
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In total 59 events in this category.