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Drug Safety Update — United Kingdom

MHRA medicines recalls and defect notifications with batch numbers, Serious Shortage Protocols, new approvals and Drug Safety Update — updated daily, automatically. Last updated: 14 Oct 2026 08:50.

All Recalls and defects4 Serious shortages (SSP) New approvals3 Drug Safety Update

Sources: we track changes based on information published by the MHRA — medicines recalls and defect notifications, Drug Safety Update and approval announcements — and the Serious Shortage Protocols published by the NHS Business Services Authority. The UK is outside the EU, so European Commission decisions are not listed here.

7 May 2025Wednesday 7 May 2025

open day ◀ ▶ 1 event · 1 important
Psychological side effects such as anxiety, low mood, sleep disturbance, poor concentration, and forgetfulness have been infrequently reported in people with cystic fibrosis treated with Kaftrio. Heal…
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24 Apr 2025Thursday 24 April 2025

open day ◀ ▶ 1 event · 1 important
Drug Safety Update Short
Healthcare professionals and patients are reminded of the risk of severe asthma attacks and increased mortality associated with overuse of SABA with or without anti-inflammatory maintenance therapy in…
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10 Apr 2025Thursday 10 April 2025

open day ◀ ▶ 1 event · 1 important
Drug Safety Update Fezolinetant▼(Veoza)
Fezolinetant treatment is associated with a risk of drug induced liver injury. New recommendations have been introduced to minimise this risk. Liver function should be monitored before and during trea…
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12 Mar 2025Wednesday 12 March 2025

open day ◀ ▶ 1 event · 1 important
Drug Safety Update Prolonged
The indication for the treatment of post-operative pain has been removed from the licences of all prolonged release opioids due to the increased risk of persistent post-operative opioid use (PPOU) and…
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26 Feb 2025Wednesday 26 February 2025

open day ◀ ▶ 1 event · 1 important
A summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices. 
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In total 59 events in this category.