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Medicine recalls, shortages and safety updates in the UK

MHRA medicines recalls and defect notifications with batch numbers, Serious Shortage Protocols, new approvals and Drug Safety Update — updated daily, automatically. Last updated: 8 Oct 2026 08:50.

All Recalls and defects3 Serious shortages (SSP) New approvals2 Drug Safety Update

Sources: we track changes based on information published by the MHRA — medicines recalls and defect notifications, Drug Safety Update and approval announcements — and the Serious Shortage Protocols published by the NHS Business Services Authority. The UK is outside the EU, so European Commission decisions are not listed here.

10 Dec 2025Wednesday 10 December 2025

open day ◀ ▶ 1 event
Class 4 defect notification · 3 products · DMRC - 37698206 · PL: 43461/0054 · Flamingo Pharma UK Ltd · amitriptyline hydrochloride
Batches: 1404515 (31/12/2025), 1404539 (31/12/2025), 1404540 (31/12/2025), 1404546 (31/12/2025), 1404721 (31/03/2026), 1404722 (31/03/2026), 1404628 (28/02/2026), 1404630 (28/02/2026), 1404631 (28/02/2026), 1404632 (28/02/2026), 1404640 (28/02/2026), 1404641 (28/02/2026), 1404629 (28/02/2026), 1404615 (31/01/2026), 1404616 (31/01/2026), 1404626 (31/01/2026), 1404627 (31/01/2026), 1404724 (31/03/2026), 1404723 (30/04/2026)
What this means, batches, details

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4 Dec 2025Thursday 4 December 2025

open day ◀ ▶ 1 event · 1 important
Idiopathic intracranial hypertension (IIH) has been very rarely reported in patients treated with mesalazine. Following a recent review, warnings for IIH are being added to the product information for…
What this means, batches, details

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2 Dec 2025Tuesday 2 December 2025

open day ◀ ▶ 1 event
MHRA approval tisotumab vedotin
As with all licensed medicines, we will continue to monitor its safety closely as it becomes more widely used
What this means, batches, details

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27 Nov 2025Thursday 27 November 2025

open day ◀ ▶ 1 event
Medicines recall Baclofen 10mg Tablets
Class 4 defect notification · DMRC - 37308281 · PL: 36722/0105 · Special Concept Development UK Limited trading as RxFarma · baclofen
Batches: EBJ25001F01 (31/01/2028), EBJ25002F01 (31/01/2028), EBJ25003F01 (31/01/2028)
What this means, batches, details

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26 Nov 2025Wednesday 26 November 2025

open day ◀ ▶ 1 event
MHRA approval inavolisib
The MHRA has today, 26 November 2025, approved inavolisib (Itovebi) for the treatment of adults with a type of breast cancer called HR-positive
What this means, batches, details

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In total 285 events.